The objective of this study was to investigate the effects of pre and post-lambing
intramuscular (i.m.) injections of vitamin E (VE) and selenium (Se) on the performance,
reproductive indices and metabolic status of Ossimi ewes. A total of 20 pregnant
ewes were divided randomly into two equal groups of ten animals. The control group (CG)
was administered 3 ml of normal saline. The treated group (TG) was administered a combination
of 5 mg of sodium selenite and 450 mg of VE twice weekly for 2 weeks pre and
post lambing. The performance, reproductive indices, colostrum and milk mineral profiles,
blood metabolites and antioxidant enzyme biomarkers were investigated in this experiment.
VE and Se supplementation had a significant effect on ewe, lamb performance,
colostrum and milk mineral profiles. The treated ewes lost less weight (0.7 kg) compared
with the ewes in the control group (3.68 kg) on 30th day postpartum (P<0.001). Lambs
born to treated ewes were heavier than those born to control ewes (4.47 kg vs 3.99 kg,
respectively), gained more daily weight quickly (268.66 vs. 226.00 g, respectively,
P<0.001) and weighed more on 30th day post-lambing (12.53 vs. 10.77 kg, respectively,
P<0.001). Treated ewes had higher concentrations of blood glucose, total protein, total
cholesterol, antioxidant enzyme biomarkers, and lower concentrations of serum non-esterified
fatty acids (NEFA). VE and Se supplementation had a significant effect (P<0.05)
on postpartum reproductive performance of ewes in terms of fast uterine involution, earlier
resumption of ovarian function and ovulation with large size ovulatory follicles, and
greater numbers of small, medium, and large-sized follicles. In conclusion, VE and Se
supplementation during late gestation and early lactation could be considered an effective
strategy for minimizing the weight loss of ewes, enhancing lamb performance, the antioxidant
and metabolic status, which improves the reproductive performance of Ossimi
ewes.