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Synthesis and Reactions of Some New Spiro{indeno[1,2-b]pyran-4,3’-
indolines}

Research Authors
Maher F. El-Zohry, Yasser A. Elossaily, Thanaa A.
Mohamed and Essam M. Hussein
Research Abstract

Indan-1,3-dione (1) reacted with 3-dicyanomethylidene-2-oxoindolines
(2a-c) in refluxed ethanol to afford 2-amino-3-cyanospiro{5H-indeno[1,2-b]
pyrane-4,3'-(1’-substitutedindoline)}-2’,5-diones (3a-c) which underwent
different reactions to afford new spiro{indeno[2',1':5,6] pyrano[2,3-d]pyrimidine-
5,3'-(1’-substitutedindoline)} (4a,b)-(12a,b) which are analogues of some
reported biologically active spiropolycyclic compounds.

Research Department
Research Journal
Heterocycles
Research Rank
1
Research Vol
Vol. 75 No. 4
Research Year
2008
Research Pages
955-963