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Novel Syntheses of Some New 3,4-Dihydrospiro{benzimidazo[1,2-a]
pyridine-3,3'-indolin}-2'-one Derivatives

Research Authors
Maher F. El-Zohry, Thanaa
A. Mohamed, and Essam M. Hussein
Research Abstract

2-Methylbenzimidazole 1 reacted with 3-dicyanomethylidine-
1-ethyl-2-oxoindoline 2 in ethyl acetate to
afford 1-amino-2-cyano-3,4-dihydro-10-ethylspiro{benzimidazo[
1,2-a]pyridine-3,30-indolin}-20-one 6, which was
used as a key intermediate in the synthesis of fused
spiropolyheterocyclic derivatives of benzimidazopyridopyrimidine
and/or benzimidazonaphthyridine nucleus
incorporating an indoline moiety

Research Department
Research Journal
Monatshifte fur Chemie
Research Rank
1
Research Vol
Vol 140, No. 3
Research Website
http://www.springerlink.com/content/p706u94823h03010/
Research Year
2009
Research Pages
pp. 265-272