Highly selective spectrofluorimetric detection of Fe3+ ions in acidic medium is developed using
novel fluorescent sensor, namely 4-(2-(3-Methyl-5-oxo-1-tosyl-1H-pyrazol-4(5H)-ylidene) hydrazinyl)-N-
(pyrimidin-2-yl) benzenesulfonamide (PHBS-sensor), which gives an selective fluorescence quenching response at λEmission 379 nm. The factors affecting fluorescence detection process, such as the pH, solvent
type, buffer type, probe concentration, reaction time and co-existing ions were systematically studied and
optimized. Theoretical modeling of Fe3+ monitoring through DFT calculation was investigated to display
the mechanism of PHBS-Fe3+ complexation. The proposed PHBS-sensor can detect Fe3+ ions at ultra-trace
levels with limit of detection 1.7 × 10−5 M. Moreover, this applied method was effectively utilized for the
monitoring/detection of Fe3+ ions in real water, such as ground, tap and Nile river water, and pharmaceutical samples, such as hard gelatin capsule and syrup.
Research Department
Research Journal
Journal of Molecular Structure
Research Publisher
ELSEVIER
Research Rank
1
Research Vol
1225
Research Website
https://www.sciencedirect.com/science/article/pii/S0022286020314964
Research Year
2021
Research Member
Research Abstract