Few studies have assessed knowledge and attitude about electroconvulsive therapy among caregivers of psychiatric patients in Egypt. This study aimed to assessment of knowledge and attitude about electroconvulsive therapy among caregivers of patients with psychiatric disorders. Subjects and methods: The studied sample included 450 caregivers of patients; 286 were male and 164 female. They were assessed through scale measures knowledge and attitudes about Electroconvulsive therapy (ECT). Results: 50.4 % of the participants did not receive information about ECT. High percentages of participants have correct knowledge and held positive attitudes towards ECT. The main significant factor affecting their knowledge and attitudes was the previous experience of their patients with ECT. Conclusion and recommendation: Inspite of their defective knowledge, caregivers of patients have correct knowledge and held positive attitudes towards ECT. Mental health providers have to spend more time to give information to caregivers and patients about ECT.