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Impact of Variable Types of Preconditioning Upon Inotropic Score in Adult Patients Undergoing Cardiac Valve Replacement Surgery: A Randomized Clinical Trial

Research Authors
MAHMOUD ABD EL-AZEZ, M.D.*; EMAD Z. KAMEL, M.D.*; MOHAMED MAHMOUD, M.D.** and SALMA I. AHMED, M.Sc
Research Journal
Med. J. Cairo Univ
Research Member
Research Publisher
NULL
Research Rank
2
Research Vol
Vol. 86, No. 5
Research Website
NULL
Research Year
2018
Research_Pages
2361-2365
Research Abstract

Background: The objective of this study was to validate the impact of cardiac preconditioning (ischemic versus pharmacological) upon postoperative inotropic score in adult patient undergoing open heart surgery.
Aim of Work: Is to validate the impact of Sevoflurane versus ischemic & Sevoflurane pc upon postoperative inotropic score in adult patient undergoing open heart surgery.
Material and Methods: Thirty ASA II-III adult undergoing open heart surgery were included in the study. They were randomly allocated into2 groups, Group A (15 patients). Anaesthetized by Sevoflurane as a pharmacologic preconditioner, Group B (15 patient) ischemic preconditioning was done after induction and before cardiopulmonary bypass by inflation the cuff of blood pressure above 200mmhg in the lower limb every 5min for 3 cycles.
Results: Non significant difference between the two groups regarding to the inotropic score and ICU stay.
Conclusion: Both ischemic and pharmacological cardiac preconditioning could offer some sort of cardiac protection reflected upon inotropic score.