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Low Glutathione Peroxidase Activity Levels in Patients with Vitiligo.

Research Authors

Zedan H, Abdel-Motaleb AA, Kassem NM, Hafeez HA, Hussein MR.
Research Journal
J Cutan Med Surg. 2015 Mar;19(2):144-8. doi: 10.2310/7750.2014.14076. Epub 2015 Mar 11.
Research Rank
1
Research Vol
19(2)
Research Year
2015
Research_Pages
144-8
Research Abstract

Background: Vitiligo is an idiopathic skin disease characterized by white areas on the skin
due to loss of the functional melanocytes, with possible involvement of oxidative stress.
Glutathione peroxidase (GPx) is an antioxidant enzyme that protects cells against oxidative
damage. Aim: To examine serum GPx levels in patients with vitiligo and to relate the findings
to the clinical features. Patients and Methods: The study group included 60 patients with
vitiligo and 30 matching healthy controls. GPx activity was evaluated using enzyme-linked ..