Climate change and global warming have become the most significant challenges to the 15agricultural production worldwide, especially in arid and semiarid areas. The main purpose of plant 16breeding programs now is to produce a genetically wide range of genotypes that canwithstand the 17adverse effects of climate change. Moreover, farmers now have to reallocate their cultivars due to 18their ability to tolerate unfavorable conditions. During this study, two field experiments and climate 19analysis based on 150 years of data were done to reallocate some genotypes of bread wheat in re- 20spect to climate change based on their performance under drought stress conditions. Climatic data 21indicate that there is an increase in temperature overall Egyptian sites coupled with in addition to 22some changes in rain amount. Among the tested cultivars, cultivar Giza 160 was the perfect one, 23while, cultivar Masr 03 was the weakest one. Susceptibility indices are a good tool for discovering 24the superior genotypes under unfavorable conditions and interestingly, some cultivars with high 25performance were among the superior cultivars in more than one of the tested traits in this study. 26Finally, combining the climatic data and the experimental data, we can concluded that, cultivars 27Giza 160 and Sakha 94 are suitable for growning in zones with harsh environments, such as the 28eastern desert and southern Egypt. While, cultivars Gemmeza 11, Sahel 01, Sakha 98, Sids 12, and 29Sakha 93 are suitable for growning in zones with good growing conditions, such as Delta and 30northern Egypt.